TEXATEL-AM ( Telmisartan 40mg + Amlodipine 5mg )

Description

TEXATEL-AM ( Telmisartan 40mg + Amlodipine 5mg )

TEXATEL-AM combines Telmisartan and Amlodipine to offer synergistic blood pressure control, targeting both vascular resistance and volume overload. This dual therapy helps manage blood pressure more effectively than monotherapy, with a better side effect profile.

Indications:

• Essential Hypertension

• Stage 1 & 2 Hypertension

• High-risk cardiac patients requiring combination therapy

• Hypertension with comorbid conditions (e.g. diabetes, nephropathy)

Mechanism of Action:

• Telmisartan: Blocks angiotensin II receptors, leading to vasodilation and reduced aldosterone effects.

• Amlodipine: Inhibits calcium influx in vascular smooth muscle, promoting arterial dilation.

Together, they:

• Lower peripheral vascular resistance

• Improve arterial compliance

• Reduce cardiac workload and afterload

Key Benefits:

• Once-daily dosing for 24-hour BP control

• Reduces risk of stroke, MI, and heart failure

• Renal protective effect – suitable for hypertensive diabetics

• Minimized side effects compared to high-dose monotherapy

• Well-tolerated in elderly and long-term users